WebOct 30, 2024 · Although several microRNAs regulate macrophage polarization, the role of the microRNA-generating enzyme Dicer in macrophage activation during … WebMay 24, 2024 · The enzyme Dicer cleaves long precursors into short RNA molecules called microRNAs. A new study reveals how Dicer enhances energy metabolism and reduces …
Suppression of microRNA activity amplifies IFN–induced …
WebMay 2, 2014 · Cigarette smoke exposure increases conjugation of SUMO chains to the protein DICER. A, alveolar macrophages from nonsmokers were exposed to 2% CSE in vitro for 6 h. Whole cell lysates were isolated, and 500 μg of protein was used for immunoprecipitation using an anti-DICER antibody. The resulting samples were divided … WebStudy with Quizlet and memorize flashcards containing terms like 1) Innate immunity ________. A) is the first, and most general, mechanism of protection against pathogens B) depends on an infected animal's previous exposure to a pathogen C) is based on recognition of antigens that are specific to a pathogen D) is found only in vertebrates … philippe tassy md
Macrophage Dicer promotes tolerogenic apoptotic cell …
WebMar 26, 2024 · In contrast, Alemdehy et al (2012) deleted DICER using a C/EBPα–Cre deleter in vivo and observed a block of monocyte, macrophage, and DC development at the GMP stage (Alemdehy et al, 2012). The discrepancy to our results, which show intact macrophage differentiation yet impaired proliferation, may be explained by the use of an … WebNov 1, 2024 · Macrophage-specific Dicer knockout (KO) mice were used to determine the roles of microRNA generated in macrophages in adipose tissue remodeling induced by the β3-adrenergic receptor agonist CL316,243 (CL). RNA-seq was performed to characterize microRNA and mRNA expression profiles in isolated macrophages and … WebMay 21, 2024 · Macrophage Dicer promotes tolerogenic apoptotic cell clearance and immune tolerance by inhibiting pentose phosphate pathway activity Cell Mol Immunol. 2024 Jul;18(7):1841-1843. doi: 10.1038/s41423-021-00693-w. Epub 2024 May 18. Authors Qiangdongzi Mao # 1 ... trulia watertown ma